![]() ![]() Cafe Kaanapali, a Hawaiian coffee house, has been doing well since it opened in the space vacated by Caffe Centro but it doesn’t attract many fans of the Italian ingredients and local and international wines in which Traverso’s has long specialized. ![]() When Sweet T’s Restaurant + Bar opens in the space sometime later this month, it will feature southern cuisine. The restaurant brought customers to the center and Traverso’s provided Italian wines for Santi’s monthly Supper Club dinners. The shuttering of Santi, the Italian restaurant that shared a wall with the beloved market, was a blow, too. ![]() The move to Fountaingrove, combined with both a struggling economy and the economic troubles of the property’s owner, Clem Carinalli, forced the difficult decision. It was a big decision, a difficult decision, for he and his son Michael, who have been at the helm of the family market since Bill Traverso, George’s cousin and Michael’s uncle, retired. “The last two years have been a real struggle,” George Traverso told me when he called yesterday with the news. The sale will likely be final sometime shortly before Thanksgiving. Traverso’s Gourmet Foods & Liquors, Inc., which relocated from downtown Santa Rosa to Fountaingrove Village a couple of years ago, is in escrow. It is with a sad and very heavy heart that I pass on news that I received yesterday from George Traverso. Its absence will leave a huge hole in Santa Rosa. As you can see from the comments at the end of this post, this market is truly loved. UPDATE: This afternoon, George and Michael Traverso sent an email to their customer list announcing the sale of their historic store. There’s a very sweet remembrance posted a couple of days ago. There are 3 professionals named 'George Traverso', who use LinkedIn to exchange information, ideas, and opportunities. We anticipate that this device could be used to treat metabolic, GI, and neuropsychiatric disorders noninvasively with minimal off-target effects.Spring Update: I continually hear from people who are either just learning of Traverso’s closure late last year, who are struggling in the aftermath of its closure or who what to share a special memory, which is why I have reposted this. View the profiles of professionals named 'George Traverso' on LinkedIn. ![]() FLASH can be orally administered to modulate GI hormones and is safely excreted with no adverse effects in porcine models. We characterized the stimulation parameters for modulation of various GI hormones in a porcine model and applied these parameters to an ingestible capsule system. Drawing inspiration from Moloch horridus, the "thorny devil" lizard with water-wicking skin, we developed a capsule surface capable of displacing fluid. Here, we report the development of a bioinspired ingestible fluid-wicking capsule for active stimulation and hormone modulation (FLASH) capable of rapidly wicking fluid and locally stimulating mucosal tissue, resulting in systemic modulation of an orexigenic GI hormone. Stimulating mucosal tissue remains challenging because of the presence of gastric and intestinal fluid, which can influence the effectiveness of local luminal stimulation. Electrical stimulation of the gastrointestinal (GI) tract, however, has generally required invasive intervention for electrode placement on serosal tissue. Electrical stimulation has also been used to attempt to modulate the gut-brain axis with greater spatial and temporal resolution. Such approaches, however, are associated with off-target effects or post-procedure recovery time and expose patients to substantial risks. Various pharmaceuticals and surgical interventions, such as motility agents and bariatric surgery, are used to modulate this axis. The gut-brain axis, which is mediated via enteric and central neurohormonal signaling, is known to regulate a broad set of physiological functions from feeding to emotional behavior. ![]()
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